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Medicine for Policymakers

Vaccines, Immunity, Whooping Cough, and Mumps

Amesh A. Adalja

Biosecurity and Bioterrorism: Volume 9, Number 1, 2011. © Mary Ann Liebert, Inc. DOI: 10.1089/bsp.2011.0212


Introduction: Vaccinations protect people against a variety of diseases, but vaccination is not always a panacea, because its effects are not permanent. Over time, the antibodies that are produced by a vaccine—and that protect against disease—may decrease in number and may fall below the threshold needed to protect against infection. Recent outbreaks of whooping cough and mumps are examples in which waning immunity from earlier vaccinations coupled with falling vaccination rates in the population have produced conditions that foster the spread of disease.  

Note: Full article available on publisher's website.