Table 1. BSL-4 Laboratories in the United States | ||||
| Institution | Name of the Laboratory | Funds Allocated | Operational Status | Other Information |
| Centers for Disease Control and Prevention (Atlanta, GA) | CDC Special Pathogens Branch, Emerging Infectious Diseases Laboratory http://www.cdc.gov/ncidod/ dvrd/spb/mnpages/ whoweare.htm#what | $214 million to complete the Emerging Infectious Diseases Laboratory in October 200526* | New facility opened in 2005; prior lab opened in 198826 | |
| USAMRIID (Ft. Detrick, MD) | http://www.usamriid.army.mil | $6 million upgrade to BSL-4 facilities in 2005; expansions projected to begin in 2006 | 1969;estimated completion date for upgrades is 201227 | |
| Southwest Foundation for Biomedical Research (San Antonio, TX) | BSL-4 Laboratory, Department of Virology and Immunology http://www.sfbr.org/pages/ virology_index.php | As of 2005, endowment exceeds $80 million,28 70% funded by competitive peer-reviewed NIH grants, 12% private endowments. | Gloveboxes since the 1970s;29 went to full biocontainment in 1999; opened in March 200030 | Conducts classified research; also has a national primate research center.30 Serves as part of the BSL-4 Core of the NIAID Western Regional Center of Excellence in Biodefense.31 |
| University of Texas Medical Branch (Galveston, TX) | UTMB Robert E. Shope, MD, BSL-4 Laboratory http://www.utmb.edu/ CBEID/safety.shtml | $15.5 million32 | June 200432 | Serves as part of the BSL-4 Core of the NIAID Western Regional Center of Excellence in Biodefense.31 |
| Georgia State University (Atlanta, GA) | Viral Immunology Center http://www.cas.gsu.edu/units/ default.aspx?unit= biotech§ion=viral | NIH grants,33 National Center for Research Resources (NCRR) | operational | |
| Virginia Commonwealth University (Richmond, VA) | Virginia Division of Consolidated Laboratory Services (DCLS) http://dcls.dgs.state.va.us/ | $63 million to complete BSL-4 facilities building34 | operational | |
| Department of Homeland Security (Ft. Detrick, MD) | National Biodefense Analysis and Countermeasures Center (NBACC) http://www.dhs.gov/xres/labs/ gc_1166211221830.shtm | $128 million appropriated over FY2003–2005; estimated construction cost $141 million35 | Broke ground June 2006; planned opening in 200838 | Governed by DHS Science and Technology Directorate; will conduct bioforensics and biological threat characterization.36 The NBACC facility will provide biocontainment laboratory space for the National Bioforensic Analysis Center (NBFAC) and the Biological Threat Characterization Center (BTCC).37 |
| National Institute of Allergy and Infectious Diseases (Hamilton, MT) | Rocky Mountain Laboratory (RML) Integrated Research Facility http://www3.niaid.nih.gov/about/ organization/dir/rml/ integratedResearchFacility.htm | $66.5 million budgeted by Congress38 | Construction began in 2004; slated for occupancy in 200739 | |
| National Institute of Allergy and Infectious Diseases and University of TX Medical Branch (Galveston, TX) | Galveston National Biocontainment Laboratory http://www.utmb.edu/ GNL/faqs/3.shtml | Total anticipated cost: $167 million ($110 million funded by NIH; UTMB to provide remainder) Estimated annual operating costs: $20 million+40 | Projected opening date: June 200841 | To study anthrax, plague, hemorrhagic fevers (such as Ebola), typhus, West Nile virus, influenza, drug-resistant TB, etc.42 |
| NIAID and Boston University (Boston, MA) | BU National Center for Emerging Infectious Diseases and Biodefense http://www.bu.edu/neidl/ | $178 million ($128 million by NIAID)43 | Expected construction completion date: 200844 | |
| National Institute of Allergy and Infectious Diseases (Fort Detrick, MD) | NIAID Integrated Research Facility at Fort Detrick http://www.niaid.nih.gov/ factsheets/detrick_qa.htm | $105 million budgeted45 | Estimated completion date: summer 200827 | |
| * | See reference list for article |