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Home > Areas of Focus > 2009 H1N1 Influenza Updates
2009 H1N1 Influenza Updates
  

Latest events and ongoing analysis related to swine flu, the potential consequences of pandemic flu, health system preparations for a pandemic, and governmental policies and plans intended to cope with the pandemic swine flu threat.

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Center Publications and Issue Briefs

International Progress in Vaccine Development and Distribution (Issue Brief, 12-17-09)

Preliminary Findings: Study of the Impact of the 2009 H1N1 Influenza Pandemic on Latino Migrant Farm Workers in the U.S. (Research Brief, 11-23-09)

Licensure, Evaluation, and Adverse Event Monitoring of the 2009 H1N1 Influenza Vaccine (Issue Brief, 11-13-09)

Where Does H1N1 Influenza Information Come from? An Overview of Influenza Surveillance in the United States (Issue Brief, 11-02-09)

Public Health and Medical Responses to the 1957-58 Influenza Pandemic
Henderson DA, Courtney B, Inglesby TV, Toner E, Nuzzo JB. Public health and medical responses to the 1957-58 influenza pandemic. Biosecurity and Bioterrorism August 2009.

Pandemic Flu Preparedness: Lessons from the Frontlines
Levi J, Inglesby TV, Segal LM, Vinter S. June 2009.

Creating Situational Awareness: A Systems Approach
(by Eric Toner, June 2009)

A Closer Look at WHO Pandemic Declaration (Issue Brief, 6-11-09)

The Use of Antivirals for 2009 H1N1 Influenza Virus Infection (Issue Brief, 5-13-09)

Social Stigma Attached to “Swine Flu”—An FAQ for U.S. Elected Leaders and Health Officials (Issue Brief, 4-30-09)

FDA Emergency Use Authorizations (EUAs): What Are They and What Do They Mean for the Swine Flu Response? (Issue Brief, 4-29-09)

Can the Current Swine Flu Outbreak Be Contained? In A Word, No (Issue Brief, 4-29-09)

Border Restrictions: Not an Effective Means of Preventing the Spread of Swine Flu (Issue Brief, 4-28-09)

An Influenza Virus Naturally Can Have Multiple Genetic Sources: Why the Current Swine Flu Virus Is Not Bioterrorism (Issue Brief, 4-28-09)

Stigma: Its Harm and Its Remedy in Outbreaks Like Swine Flu (Issue Brief, 4-24-09)

See the Biosecurity News in Brief archive for ongoing coverage of news and new developments.

                 

Updates from the Clinicians' Biosecurity Network
(published during and since the Spring 2009 outbreak of H1N1 influenza A)

October 2009

CBN Report Swine Flu 09-10

Clinicians' Biosecurity Network Report archive for October 2009 swine flu updates.

  1. 2009 H1N1 Influenza Update: Cases, Hospitalizations, and Mortality (10-22-2009)

    This overview of the current status of the 2009 H1N1 influenza pandemic in the U.S. describes the epidemiology, clinical manifestations, and treatment of individuals infected with 2009 H1N1 influenza. Information is current as of October 21, 2009.
    Thu, 22 Oct 2009 20:26:26 GMThttp://www.upmc-cbn.org/report_archive/h1n1/issue_briefs/2009-10-22-H1N1-update_cases.html

   
September 2009

CBN Report Swine Flu 09-09

Clinicians' Biosecurity Network Report archive for September 2009 swine flu updates.

  1. Single-Dose Vaccination for the 2009 H1N1 Influenza A Virus (09-15-2009)

    Two studies published ahead of print in the New England Journal of Medicine provide evidence that a single dose of vaccine may be sufficient for the 2009 H1N1 influenza A.
    Tue, 15 Sep 2009 19:24:03 GMThttp://www.upmc-cbn.org/report_archive/2009/09_September_2009/cbnreport_09152009.html

  2. H1N1 Dual Infections (09-04-2009)

    As the world is currently in the midst of a WHO stage VI pandemic with the 2009 H1N1 influenza virus, it remains a possibility that this virus could reassort with other flu strains--most notably, the WHO stage III pandemic H5N1 avian influenza virus.
    Fri, 04 Sep 2009 17:35:24 GMThttp://www.upmc-cbn.org/report_archive/2009/09_September_2009/cbnreport_09042009.html

  
August 2009

CBN Report Swine Flu 09-08

Clinicians' Biosecurity Network Report archive for August 2009 swine flu updates.

  1. Zanamivir Resistance in Influenza (08-14-2009)

    Antiviral therapy against influenza always has been plagued by the development of resistance. Unfortunately, as medical mngmnt of flu relies increasingly on antiviral therapy, resistance will become more commonplace, and may render some drugs obsolete.
    Fri, 14 Aug 2009 16:12:42 GMThttp://www.upmc-cbn.org/report_archive/2009/08_August_2009/cbnreport_08142009

    
July 2009

CBN Report Swine Flu 09-07

Clinicians' Biosecurity Network Report archive for July 2009 swine flu updates.

  1. A Novel H3N2 Influenza A Variant Emerges (07-31-2009)

    A new H3N2 variant has emerged that may be poorly matched to the 2009 seasonal flu vaccine. This could pose a risk to the elderly and to those who have been vaccinated against the pandemic strain.
    Mon, 03 Aug 2009 16:57:39 GMThttp://www.upmc-cbn.org/report_archive/2009/07_July_2009/cbnreport_07312009.html

  2. 2009 H1N1 Influenza A: Clinical Details, Antiviral Resistance, and Other Mutations (07-17-09)

    Several scientific papers have been published recently that elucidate both the spectrum of illness caused by the 2009 H1N1 influenza (A) virus and its ability to evade antiviral drugs.
    Fri, 17 Jul 2009 16:39:39 GMThttp://www.upmc-cbn.org/report_archive/2009/07_July_2009/cbnreport_07172009.html

   
June 2009

CBN Report Swine Flu 09-06

Clinicians' Biosecurity Network Report archive for June 2009 swine flu updates.

  1. Healthcare Workers at Risk for H1N1 Infection (06-19-2009)

    There have been cases of the 2009 H1N1 influenza (A) virus among healthcare workers, as detailed in the June 19, 2009 MMWR. It appears that all could have been prevented had standard infection control measures been taken.
    Mon, 06 Jul 2009 15:10:17 GMThttp://www.upmc-cbn.org/report_archive/2009/06_June_2009/cbnreport_06192009.html

  2. H7-subtype Influenza Infections: Pandemic Potential? (06-05-2009)

    However, the pandemic potential of the H7 viruses cannot be overlooked. While they are not nearly as lethal as H5N1, a pandemic need not cause mass lethality to have a significant impact around the globe.
    Fri, 05 Jun 2009 19:00:35 GMThttp://www.upmc-cbn.org/report_archive/2009/06_June_2009/cbnreport_06052009.html

   
May 2009

CBN Report Swine Flu 09-05

Clinicians' Biosecurity Network Report archive for May 2009 swine flu updates.

  1. Clinical Details of 2009 H1N1 in Hospitalized Patients (05-22-09)

    Important clinical details about the more severely affected 2009 H1N1 patients are beginning to emerge. These details of hospitalized patients are vital information for clinicians who may need to manage other patients.
    Fri, 22 May 2009 15:08:20 GMThttp://www.upmc-cbn.org/report_archive/h1n1/05-09_Swine_Flu/cbnreport_SFhospitalized_patients-05-22-09.html

  2. Clinical Details of 2009 H1N1 Influenza Cases Emerge (05-04-2009)

    As cases of 2009 H1N1 influenza continue to accrue worldwide, more clinical information has become available and is useful in guiding the medical management of these patients.
    Mon, 04 May 2009 19:43:16 GMThttp://www.upmc-cbn.org/report_archive/h1n1/05-09_Swine_Flu/cbnreport_SF8_5-04-09_AM.html

   
April 2009

CBN Report Swine Flu 09-04

Clinicians' Biosecurity Network Report archive for April 2009 swine flu updates.

  1. Can the Current Swine Flu Outbreak Be Contained? In A Word, No (04-29-2009)

    Both the WHO and CDC have concluded that is no longer possible to contain the outbreak of swine influenza. This means that it is not feasible to use border closures and/or restrictions or public health measures to limit the spread of the outbreak.
    Wed, 29 Apr 2009 18:00:00 GMThttp://www.upmc-cbn.org/report_archive/h1n1/04-09_Swine_Flu/cbnreport_SF7_4-29-09_PM.html

  2. Border Closures * Rapid Flu Tests * EUAs and Diagnostic Tests * Epi Update * Guidance from CDC * Guidance from WHO (04-28-2009)

    Center for Biosecurity Swine Flu Update (4-28-09): Rapid Flu Tests Have Limited Utility * FDA Issues Authorizations for EUAs and Diagnostic Tests * Epi Update * Updated Guidance from CDC * New Guidance from WHO
    Tue, 28 Apr 2009 18:01:00 GMThttp://www.upmc-cbn.org/report_archive/h1n1/04-09_Swine_Flu/cbnreport_SF6_4-28-09_PM.html

  3. WHO Raises Pandemic Alert Level * EU Issues Travel Advisories for United States and Mexico * Additional Cases in NYC and Other Countries * Updated Guidance from CDC (04-27-2009)

    Monday, 4-27 | 6:00 PM -- WHO Raises Pandemic Alert Level * EU Issues Travel Advisories for United States and Mexico * Additional Cases in NYC and Other Countries * Updated Guidance from CDC (Center for Biosecurity of UPMC)
    Mon, 27 Apr 2009 18:01:00 GMThttp://www.upmc-cbn.org/report_archive/h1n1/04-09_Swine_Flu/cbnreport_SF5_4-27-09_PM.html

  4. CDC/DHS Press conference; WHO pandemic alert level; epidemiology update (04-26-2009)

    Sunday, 4-26 | 7:00 PM -- CDC/DHS Press Conference; WHO pandemic alert level; Epidemiology Update
    Sun, 26 Apr 2009 18:02:00 GMThttp://www.upmc-cbn.org/report_archive/h1n1/04-09_Swine_Flu/cbnreport_SF4_4-26-09_PM.html

  5. New developments; WHO pandemic alert levels; key questions (04-25-2009)

    Media outlets are reporting this afternoon that confirmed and probable cases of the new strain of H1N1 swine influenza have been discovered in Kansas, New York, and California.
    Sat, 25 Apr 2009 18:02:00 GMThttp://www.upmc-cbn.org/report_archive/h1n1/04-09_Swine_Flu/cbnreport_SF3_4-25-09_PM.html

  6. Mexico cases; U.S. cases; info. CDC has confirmed; key questions (04-24-2009)

    Since earlier CBN rpt, various news articles citing officials from the WHO have reported approx. 60 fatalities and 100s cases of suspected swine flu A in humans in Mexico. Still no official confirmation of number cases or deaths.
    Fri, 24 Apr 2009 23:03:00 GMThttp://www.upmc-cbn.org/report_archive/h1n1/04-09_Swine_Flu/cbnreport_SF2_4-24-09_PM.html

  7. Swine Flu Cases Without Swine Exposure (04-24-2009)

    On 4/21/2009, the CDC described 2 cases of swine flu A (H1N1) infection in Southern CA in April. While both patients recovered uneventfully, the isolated viruses harbor novel genetic characteristics not seen in the U.S. prior to this event.
    Fri, 24 Apr 2009 14:30:00 GMThttp://www.upmc-cbn.org/report_archive/h1n1/04-09_Swine_Flu/cbnreport_SF1_4-24-09_AM.html

           

Useful Links and Resources

World Health Organization (WHO)

Centers for Disease Control and Prevention (CDC)

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